Lorraine Williamson
María Branyas, the Spanish woman who held the title of the world’s oldest woman until her passing in August 2024, lived to be 117. Her exceptionally long life has prompted scientists to explore the factors that contributed to her longevity.
Researchers analysed her genetic profile and lifestyle to understand the keys to a long and healthy life.
The role of genetics in longevity
One of the most significant factors in María’s longevity was her genetic makeup. A study by the Josep Carreras Institute and the University of Barcelona revealed that her genome was unique. Her cells functioned as if they were 17 years younger than her actual age, reducing her risk of age-related diseases and enhancing her ability to resist degenerative processes.
A healthy gut microbiome
María also had an exceptionally healthy gut microbiome, similar to that of a much younger person. A balanced microbiome strengthens the immune system and reduces inflammation, both of which are critical for longevity. Research has linked gut health to a lower risk of chronic conditions such as cardiovascular disease, diabetes, and neurodegenerative disorders.
Lifestyle and social connections
While genetics played a major role, María’s lifestyle also contributed to her longevity. She followed a Mediterranean diet rich in olive oil, fish, vegetables, fruits, and nuts—known for its cardiovascular benefits and positive effects on brain function.
Beyond diet, María lived in a peaceful environment and maintained an optimistic mindset. Studies suggest that stress reduction, social connections, and regular physical activity are essential for a long and healthy life.
Lessons from María Branyas
María’s life demonstrates that aging does not have to be accompanied by disease and decline. While genetics are an important factor, lifestyle choices such as a healthy diet, physical activity, and a positive social environment can also contribute to longevity.
Although not everyone can inherit María’s unique genetic advantages, her story provides valuable insights into how humans can improve their chances of aging healthily.